Articles 2017

Haimila K, Sulin K, Kuosmanen M, Sareneva I, Korhonen A, Natunen S, Tuimala J, Sainio S. Targeted antenatal anti-D prophylaxis program for RhD-negative pregnant women – outcome of the first two years of a national program in Finland. Acta Obstet Gynecol Scand. 2017 Oct;96(10):1228-1233. PMID: 28718198

Hyvärinen K, Ritari J, Koskela S, Niittyvuopio R, Nihtinen A, Volin L, Gallardo D, Partanen J. Genetic polymorphism related to monocyte-macrophage function is associated with graft-versus-host disease. Sci Rep. 2017 Nov 15;7(1):15666. PMID: 29142307

Ilander M, Olsson-Stromberg U, Schlums H, Guilhot J, Bruck O, Lahteenmaki H, Kasanen T, Koskenvesa P, Soderlund S, Hoglund M, Markevarn B, Sjalander A, Lotfi K, Dreimane A, Lubking A, Holm E, Bjoreman M, Lehmann S, Stenke L, Ohm L, Gedde-Dahl T, Majeed W, Ehrencrona H, Koskela S, Saussele S, Mahon FX, Porkka K, Hjorth-Hansen H, Bryceson YT, Richter J and Mustjoki S. Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia. Leukemia 2017;31(5):1108-16. PM: 27890936

Jokiranta S, Valtonen K, Kutvonen H, Ihalainen J, Halttunen T, Lappalainen M, Hiltunen-Back E. Internet-palveluun perustuvan klamydian ja tippurin kotinäytteenoton tulokset Vantaalla. Suomen Lääkärilehti 2017;72(7):419-426.

Kaartinen T, Luostarinen A, Maliniemi P, Keto J, Arvas M, Belt H, Koponen J, Loskog A, Mustjoki S, Porkka K, Yla-Herttuala S and Korhonen M. Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion. Cytotherapy 2017;19(6):689-702. PM: 28411126

Koefoed-Nielsen P, Weinreich I, Bengtsson M, Lauronen J, Naper C, Gäbel M, Sørensen SS, Wennberg L, Reisaeter AV, Møller BK; Nordic Kidney group and the Tissue Typing group in Scandiatransplant. Scandiatransplant acceptable mismatch program (STAMP) a bridge to transplanting highly immunized patients. HLA. 2017 Jul;90(1):17-24. PMID: 28449350

Kumar A, Kankainen M, Parsons A, Kallioniemi O, Mattila P, Heckman CA. The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia. BMC Genomics. 2017 Aug 17;18(1):629. PMID: 28818039

Kumbhare SV1,2, Kumar H3, Chowdhury SP2,4, Dhotre DP2, Endo A5, Mättö J6, Ouwehand AC, Rautava S, Joshi R, Patil NP, Patil RH, Isolauri E, Bavdekar AR, Salminen S, Shouche YS. A cross-sectional comparative study of gut bacterial community of Indian and Finnish children. Sci Rep. 2017 Sep 5;7(1):10555. PMID: 28874767

Larjo A, Eveleigh R, Kilpeläinen E, Kwan T, Pastinen T, Koskela S, Partanen J. Accuracy of programs for the determination of HLA alleles from NGS data. Front. Immunol. 2017 Dec 13;8:1815. PMID:29326702

Laurén E, Tigistu-Sahle F, Valkonen S, Westberg M, Valkeajärvi A, Eronen J, Siljander P, Pettilä V, Käkelä R, Laitinen S, Kerkelä E. Phospholipid composition of packed red blood cells and that of extracellular vesicles show a high resemblance and stability during storage. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jan;1863(1):1-8. Epub 2017 PMID: 28965917

Lassenius MI, Fogarty CL, Blaut M, Haimila K, Riittinen L, Paju A, Kirveskari J, Jarvela J, Ahola AJ, Gordin D, Harma MA, Kumar A, Hamarneh SR, Hodin RA, Sorsa T, Tervahartiala T, Horkko S, Pussinen PJ, Forsblom C, Jauhiainen M, Taskinen MR, Groop PH, Lehto M and FinnDiane Study Group. Intestinal alkaline phosphatase at the crossroad of intestinal health and disease – a putative role in type 1 diabetes. Journal of Internal Medicine 2017;281(6):586-600. PM: 28393441

Lindford AJ, Lauronen J, Juvonen E, Haimila K and Koljonen V. Evaluation of human leukocyte antigen sensitization in burn patients after treatment with skin allografts and transfusion of blood products. Transplant International 2017;30(3):320-2. PM: 28032376

Linjama T, Niittyvuopio R, Tuimala J, Pyörälä M, Rintala H, Rimpiläinen J, Kauppila M, Peräsaari J, Juvonen E. Platelet donor selection for HLA-immunised patients; the impact of donor-specific HLA antibody levels. Transfus Med. 2017 Oct;27 Suppl 5:375-383. PMID: 28382715

Lokki AI, Kaartokallio T, Holmberg V, Onkamo P, Koskinen L, Saavalainen P, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Villa P, Hiltunen L, Laivuori H, Meri S. Analysis of Complement C3 Gene Reveals Susceptibility to Severe Preeclampsia. Frontiers in Immunology 2017;8(article589). PMID: 28611769

Lähteenmäki K, Wacklin P, Taskinen M, Tuovinen E, Lohi O, Partanen J, Mättö J, Vettenranta K. Haematopoietic stem cell transplantation induces severe dysbiosis in intestinal microbiota of paediatric ALL patients. Bone Marrow Transplant. 2017 Oct;52(10):1479-1482. PMID: 28783141

Miettinen J, Tainio J, Jahnukainen T, Pakarinen M, Lauronen J, Jalanko H. Anemia and low-grade inflammation in pediatric kidney transplant recipients. Pediatric  Nephrology 2017;32(2):347-58. PM: 27576676

Muhonen V, Narcisi R, Nystedt J, Korhonen M, van Osch GJ and Kiviranta I. Recombinant human type II collagen hydrogel provides a xeno-free 3D micro-environment for chondrogenesis of human bone marrow-derived mesenchymal stromal cells. Journal of Tissue Engineering and Regenerative Medicine 2017;11(3):843-54. PM: 25643647

Niittymäki P, Arvas M, Larjo A, Mattila P, Ihalainen J, Syrjälä M, Castrén J, Partanen J. Retrospective analysis of capillary hemoglobin recovery in nearly 1 200 000 blood donor returns. Blood Advances, 2017; 1: 961-7. PMID: 29296737

Nissilä E, Douillard FP, Ritari J, Paulin L, Järvinen HM, Rasinkangas P, Haapasalo K, Meri S, Jarva H, de Vos WM. Genotypic and phenotypic diversity of Lactobacillus rhamnosus clinical isolates, their comparison with strain GG and their recognition by complement system. PLoS One 2017;12(5):e0176739. PM: 28493885

Pasumarthy KK, Doni Jayavelu N, Kilpinen L, Andrus C, Battle SL, Korhonen M, Lehenkari P, Lund R, Laitinen S, Hawkins RD. Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements. Stem Cell Reports. 2017 Sep 12;9(3):999-1015. PMID: 28844656

Peräsaari JP, Jaatinen T, Merenmies J. Donor-specific HLA antibodies in predicting crossmatch outcome: Comparison of three different laboratory techniques. Transpl Immunol. 2017 Nov 20. PMID: 29157597

Polvi A, Peräsaari J, Linjama T, Saarinen T, Koskela S, Voorter CEM, Jaatinen T. Description of four new HLA alleles in the Finnish population: A*03:283N, A*68:167, C*03:327, C*03:361. HLA. 2018 Jan;91(1):61-62. Epub 2017 Oct 24. PMID:29030950

Porkka K, Niemi M, Leppä E, Västrik I, Partanen J, Ihalainen J, Jokiranta S, Pöllänen P. Genomilääketieteen sovelluksia sairauksien hoidossa. Duodecim 2017;133(8):782-90.

Puhka M, Nordberg ME, Valkonen S, Rannikko A, Kallioniemi O, Siljander P and Af Hällström TM. KeepEX, a simple dilution protocol for improving extracellular vesicle yields from urine. European Journal of Pharmaceutical Sciences 2017;98(February):30-39. PM: 27771514

Puhka M, Takatalo M, Nordberg ME, Valkonen S, Nandania J, Aatonen M, Yliperttula M, Laitinen S, Velagapudi V, Mirtti T, Kallioniemi O, Rannikko A, Siljander PR, Af Hällström TM. Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes. Theranostics. 2017 Aug 23;7(16):3824-3841. PMID: 29109780

Ryhänen S, Nystedt J, Korhonen M, Vettenranta K. Haploidenttisten kantasolujen siirrot lapsille alkavat Suomessa. Duodecim 2017;133(3):231-3.

Sainio S, Javela K, Tuimala J, Haimila K. Maternal HLA genotyping is not useful for predicting severity of fetal and neonatal alloimmune thrombocytopenia. British  Journal of Haematology 2017;176(1):111-7. PM: 27748520

Salmenniemi U, Itälä-Remes M, Nystedt J, Putkonen M, Niittyvuopio R, Vettenranta K, Korhonen M. Good responses but high TRM in adult patients after MSC therapy for GvHD. Bone Marrow Transplantation 2017;52(4):606-8. PM: 2794178

Savola P, Kelkka T, Rajala HL, Kuuliala A, Kuuliala K, Eldfors S, Ellonen P, Lagström S, Lepistö M, Hannunen T, Andersson EI, Khajuria RK, Jaatinen T, Koivuniemi R, Repo H, Saarela J, Porkka K, Leirisalo-Repo M, Mustjoki S. Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis. Nat Commun. 2017 Jun 21;8:15869. PMID: 28635960

Strunk D1, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Öller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schäfer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, Lόpez-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K. International Forum on GMP-grade human platelet lysate for cell propagation: summary. Vox Sang. 2017 Oct 26. PMID: 29076169

Strunk D, Lozano M, Marks DC, Loh YS, Gstraunthaler G, Schennach H, Rohde E, Laner-Plamberger S, Öller M, Nystedt J, Lotfi R, Rojewski M, Schrezenmeier H, Bieback K, Schäfer R, Bakchoul T, Waidmann M, Jonsdottir-Buch SM, Montazeri H, Sigurjonsson OE, Iudicone P, Fioravanti D, Pierelli L, Introna M, Capelli C, Falanga A, Takanashi M, López-Villar O, Burnouf T, Reems JA, Pierce J, Preslar AM, Schallmoser K. International Forum on GMP-grade human platelet lysate for cell propagation. Vox Sang. 2017 Oct 25. PMID: 29071726

Sundquist E, Kauppila JH, Veijola J, Mroueh R, Lehenkari P, Laitinen S, Risteli J, Soini Y, Kosma VM, Sawazaki-Calone I, Macedo CC, Bloigu R, Coletta RD and Salo T. Tenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups. British Journal of Cancer 2017;116(5):640-8. PM: 28095396

Tigistu-Sahle F, Lampinen M, Kilpinen L, Holopainen M, Lehenkari P, Laitinen S and Käkelä R. Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells. Journal of Lipid Research 2017;58(1):92-110. PM: 27856675

Tripathi SK, Chen Z, Larjo A, et al. (Wijmenga C, Lähdesmäki H and Lahesmaa R). Genome-wide Analysis of STAT3-Mediated Transcription during Early Human Th17 Cell Differentiation. Cell Reports 2017;19:1888–1901. PMID: 28564606

Valkonen S, van der Pol E, Boing A, Yuana Y, Yliperttula M, Nieuwland R, Laitinen S and Siljander PR. Biological reference materials for extracellular vesicle studies. European Journal of Pharmaceutical Sciences 2017;98(February):4-16. PM: 27622921

Vuk T, Magnussen K, De Kort W, Follea G, Liumbruno GM, Schennach H, Vandewalle G, Compernolle V, Masharova N, Karakatsiani G, Argyrou I, Rehacek V, Khanirzajeva G, Castrén J, Danic B, Djoudi R, Woimant G, Mueller MM, Politis C, Vaglio S, Daugavvanaga A, Vilutyte E, Faber JC, Borg-Aquilina D, Van Den Burg P, Bokhorst A, Poglod R, Antoniewicz-Papis J, Muon M, Burta OL, Rosochova J, Mali P, Vesga MA, Schneider K, Norda R and Anderson N. International forum: an investigation of iron status in blood donors. Blood Transfusion 2017;15(1)20-41. PM: 27643753

Ylinen E, Salmela L, Peräsaari J, Jaatinen T, Tenca A, Vapalahti O, Färkkilä M, Jalanko H and Kolho KL. Human leucocyte antigens B*08, DRB1*03 and DRB1*13 are significantly associated with autoimmune liver and biliary diseases in Finnish children. Acta Paediatrica 2017;106(2):322-6. PM: 27759901

Yohannes DA, Freitag TL, de Kauwe A, Kaukinen K, Kurppa K, Wacklin P, Mäki M, Arstila TP, Anderson RP, Greco D, Saavalainen P. Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease. Sci Rep. 2017 Dec 21;7(1):17977. PMID: 29269859

CONSORTIUM COLLABORATION

Cooper DJ, McQuilten ZK, Nichol A, Ady B, Aubron C, Bailey M, Bellomo R, Gantner D, Irving DO, Kaukonen KM, McArthur C, Murray L, Pettilä V, French C; TRANSFUSE Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults. N Engl J Med. 2017 Nov 9;377(19):1858-1867. PMID: 28952891